Congenital amputation is birth without a limb or limbs, or without a part of a limb or limbs
Congenital amputation is the absence of a fetal limb or fetal part at birth. This condition may be the result of the constriction of fibrous bands within the membrane that surrounds the developing fetus (amniotic band syndrome) or the exposure to substances known to cause birth defects (teratogenic agents). Other factors, including genetics, may also play a role. It is known to be caused by blood clots forming in the fetus while in utero (vascular insult) and from amniotic band syndrome: fibrous bands of the amnion that constrict fetal limbs to such an extent that they fail to form or actually fall off due to missing blood supply. Congenital amputation can also occur due to maternal exposure to teratogens during pregnancy.
Congenital amputation is a rare condition where a child is born with one or more missing limbs. There are various causes of congenital amputation, but in most cases, there are no known ways to prevent it. Children with congenital amputation can adapt and lead full, active lives with the right support, such as prosthetic devices, physical therapy, occupational therapy, and psychological support. Women can reduce their risk of having a child with congenital amputation by managing chronic health conditions, avoiding harmful substances, receiving regular prenatal care, and seeking genetic counselling if they have a family history of birth defects.